{"id":135903,"date":"2021-03-04T07:31:16","date_gmt":"2021-03-04T10:31:16","guid":{"rendered":"http:\/\/diariotextual.com\/inicio\/?p=135903"},"modified":"2021-03-04T10:37:53","modified_gmt":"2021-03-04T13:37:53","slug":"detectaron-en-el-pais-la-presencia-de-las-peligrosas-cepas-del-reino-unido-manaos-y-rio","status":"publish","type":"post","link":"https:\/\/diariotextual.com\/inicio\/index.php\/2021\/03\/04\/detectaron-en-el-pais-la-presencia-de-las-peligrosas-cepas-del-reino-unido-manaos-y-rio\/","title":{"rendered":"Detectaron en el pa\u00eds la presencia de las peligrosas cepas del Reino Unido, Manaos y R\u00edo"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">La vigilancia de las variantes de SARS-CoV-2 realizada sobre un total de 626 muestras de la ciudad de Buenos Aires, la provincia de Buenos Aires, C\u00f3rdoba y la ciudad de Santa Fe determin\u00f3 la presencia de\u00a0<strong>\u201ctres variantes de inter\u00e9s epidemiol\u00f3gico mundial en nuestro pa\u00eds\u201d: la del Reino Unido, la de Manaos y la de R\u00edo de Janeiro.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A la vez, no se detect\u00f3 la combinaci\u00f3n de mutaciones caracter\u00edsticas de la variante sudafricana, seg\u00fan el \u00faltimo reporte del Proyecto Argentino Interinstitucional de gen\u00f3mica de SARS-CoV-2 (Proyecto Pa\u00eds).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cSe detect\u00f3 la combinaci\u00f3n de mutaciones caracter\u00edstica de la variante 501Y.V3 (Manaos) en dos muestras, y la de la variante 501Y.V1 (Reino Unido) en una muestra, mientras que tambi\u00e9n se detect\u00f3 la mutaci\u00f3n S_E484K -caracter\u00edstica de la variante P.2 (R\u00edo de Janeiro)- en 15 muestras y la mutaci\u00f3n S_E484Q en un caso\u201d, se indic\u00f3 en el resumen.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Tambi\u00e9n se precis\u00f3 que en uno de los casos que present\u00f3 la variante de Manaos tuvo antecedente de viaje a Pipa, Brasil, y el otro habr\u00eda sido contacto de otro viajero, tambi\u00e9n procedente de Brasil.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En cambio, el caso de la variante del Reino Unido \u201chabr\u00eda sido adquirido en la comunidad\u201d, estimaron los investigadores.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cLa mutaci\u00f3n S_E484K \u00fanicamente en combinaci\u00f3n con D614G se detect\u00f3 en 15 muestras (18,5 %), lo que sugiere que \u00e9stas pueden corresponder a casos de infecci\u00f3n por la variante P.2 (R\u00edo de Janeiro) -en circulaci\u00f3n comunitaria en nuestro pa\u00eds- que deber\u00e1n confirmarse por secuenciaci\u00f3n y an\u00e1lisis del genoma completo\u201d, se explic\u00f3.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Y agregaron que de los casos con la mutaci\u00f3n E484K, once corresponden a casos del Municipio de la Matanza, provincia de Buenos Aires, y cuatro a muestras provienen de la CABA. Adem\u00e1s, se observ\u00f3 un caso con la mutaci\u00f3n S_E484Q, proveniente de la CABA.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Hasta el momento, sobre un total de 626 muestras analizadas a trav\u00e9s de la vigilancia activa de variantes, la del Reino Unido se identific\u00f3 en cuatro casos (0,6 %), la de Manaos en dos (0,3 %) y la mutaci\u00f3n S_E484K en forma aislada -compatible con P.2 (R\u00edo de Janeiro)- en 43 casos (6,9 %) y la mutaci\u00f3n S_L452R\/Q\/M en siete.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En cuanto al linaje P.2 (R\u00edo de Janeiro), se confirm\u00f3 su presencia en siete casos, correspondientes a circulaci\u00f3n comunitaria en AMBA, a partir de varias introducciones al pa\u00eds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cLa mutaci\u00f3n S_E484K\/Q -en ausencia de las mutaciones en Spike caracter\u00edsticas de las otras variantes- fue identificada en un total de 43 casos (que incluyen a los siete de variante P.2 mencionados previamente)\u201d, continu\u00f3 el reporte del Proyecto Pa\u00eds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Durante las \u00faltimas semanas epidemiol\u00f3gicas se observ\u00f3 un aumento de la frecuencia de esta mutaci\u00f3n, \u201clo que es indicativo de mayor dispersi\u00f3n en nuestra poblaci\u00f3n\u201d.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En un grupo de siete muestras se detect\u00f3 la mutaci\u00f3n S_L452R\/Q\/M, todas sin nexo epidemiol\u00f3gico entre s\u00ed, ni antecedentes de viaje, por lo que corresponder\u00edan a casos de circulaci\u00f3n comunitaria.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u201cSe ha observado que mutaciones en esta posici\u00f3n se asociar\u00edan con posible escape inmunol\u00f3gico y pueden presentarse en diversos linajes de reciente emergencia a nivel mundial, por lo que estos genomas se estudiar\u00e1n m\u00e1s exhaustivamente en el pr\u00f3ximo per\u00edodo de an\u00e1lisis\u201d, concluye el informe.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Por \u00faltimo, se afirm\u00f3 que el Consorcio Argentino Interinstitucional de Gen\u00f3mica de SARS-CoV-2 del Proyecto Pa\u00eds continuar\u00e1 realizando la vigilancia molecular \u201csobre los casos de circulaci\u00f3n comunitaria con la estrategia planteada, a fin de monitorear con rapidez la presencia de variantes de inter\u00e9s epidemiol\u00f3gico internacional y la emergencia de variantes virales locales\u201d.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La vigilancia de las variantes de SARS-CoV-2 realizada sobre un total de 626 muestras de la ciudad de Buenos Aires, la provincia de Buenos Aires, C\u00f3rdoba y la ciudad de&hellip;<\/p>\n","protected":false},"author":3,"featured_media":133968,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1,12],"tags":[],"class_list":["post-135903","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-es-noticia","category-sociedad"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Detectaron en el pa\u00eds la presencia de las peligrosas cepas del Reino Unido, Manaos y R\u00edo - Diario Textual<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/diariotextual.com\/inicio\/index.php\/2021\/03\/04\/detectaron-en-el-pais-la-presencia-de-las-peligrosas-cepas-del-reino-unido-manaos-y-rio\/\" \/>\n<meta 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