{"id":145676,"date":"2021-05-12T13:56:46","date_gmt":"2021-05-12T16:56:46","guid":{"rendered":"http:\/\/diariotextual.com\/inicio\/?p=145676"},"modified":"2021-05-12T13:56:47","modified_gmt":"2021-05-12T16:56:47","slug":"detectaron-la-cepa-manaos-en-la-ciudad-rionegrina-de-general-roca","status":"publish","type":"post","link":"https:\/\/diariotextual.com\/inicio\/index.php\/2021\/05\/12\/detectaron-la-cepa-manaos-en-la-ciudad-rionegrina-de-general-roca\/","title":{"rendered":"Detectaron la cepa Manaos en la ciudad rionegrina de General Roca"},"content":{"rendered":"\n<p>R\u00edo Negro confirm\u00f3 esta ma\u00f1ana que la <strong>cepa de la variante \u201cManaos\u201d fue detectada en la ciudad de General Roca<\/strong>, tras el an\u00e1lisis de secuenciaci\u00f3n gen\u00f3mica que realiz\u00f3 el Instituto Malbr\u00e1n sobre las muestras enviadas, inform\u00f3 hoy el jefe de Laboratorio del Hospital Francisco L\u00f3pez Lima, Juan Paulo Laher.<\/p>\n\n\n\n<p>A su vez, la organizaci\u00f3n Mundial de la Salud (OMS) inform\u00f3 en el \u201cDocumento de Orientaciones Previsionales\u201d emitido en enero que <strong>en el transcurso de un a\u00f1o desde la primera identificaci\u00f3n del SARS-CoV-2, se han registrado m\u00e1s de 280.000 secuencias gen\u00f3micas completas<\/strong> en bases de datos de acceso p\u00fablico.<\/p>\n\n\n\n<p>Sobre las muestras enviadas de manera aleatoria al Instituto Malbr\u00e1n, que en total fueron ocho, Laher dijo: \u201cSiempre se da prioridad a las muestras de pacientes que han venido de zonas calientes de la Argentina; o donde ya hay circulaci\u00f3n otras variantes o del exterior\u201d.<\/p>\n\n\n\n<p>La cepa Manaos es una variante de la cepa original que se caracteriza por tener mutaciones a nivel del genoma; que se ven reflejadas en alteraciones o modificaciones en prote\u00ednas determinadas del virus.<\/p>\n\n\n\n<p>\u201cEn este caso, esta mutaci\u00f3n afecta una prote\u00edna de membrana de la esp\u00edcula; lo que <strong>genera que el virus tenga mayor capacidad infectiva; y que la sintomatolog\u00eda sea m\u00e1s marcada\u201d, detall\u00f3 Laher.<\/strong><\/p>\n\n\n\n<p>En ese sentido, la OMS explic\u00f3 en el mismo informe: \u201cLa secuenciaci\u00f3n gen\u00e9tica permite leer el genoma de un virus, con ese m\u00e9todo se pueden descubrir nuevos pat\u00f3genos como sucedi\u00f3 con el SARS-CoV-2, ya que cada organismo posee una secuencia gen\u00f3mica exclusiva\u201d.<\/p>\n\n\n\n<p>\u201cEl genoma del SARS-CoV-2 codifica prote\u00ednas no estructurales, cuatro prote\u00ednas estructurales: la esp\u00edcula, la envoltura, la membrana y la nucleoc\u00e1pside y prote\u00ednas presuntamente accesorias\u201d, agreg\u00f3.<\/p>\n\n\n\n<p>\u201cPara penetrar en la c\u00e9lula hospedadora, el SARS-CoV-2 se vale de la esp\u00edcula, que se acopla a la enzima convertidora de la angiotensina de la c\u00e9lula, y la prote\u00edna de la esp\u00edcula del SARS-CoV-2, constituye un elemento crucial para la inmunidad, ya sea innata o vacunal\u201d, remarc\u00f3 el documento.<\/p>\n\n\n\n<p>La OMS aclar\u00f3 que la diversificaci\u00f3n del gen que codifica dicha prote\u00edna podr\u00eda, por tanto, influir en la eficacia de las vacunas y de los tratamientos con anticuerpos monoclonales, as\u00ed como en la inmunidad innata. \u201cCuando los virus se replican, en especial los virus de ARN como el SARS-CoV-2, se producen cambios en su genoma denominados mutaciones\u201d, a\u00f1adi\u00f3 el informe.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>R\u00edo Negro confirm\u00f3 esta ma\u00f1ana que la cepa de la variante \u201cManaos\u201d fue detectada en la ciudad de General Roca, tras el an\u00e1lisis de secuenciaci\u00f3n gen\u00f3mica que realiz\u00f3 el Instituto&hellip;<\/p>\n","protected":false},"author":5,"featured_media":88301,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1,12],"tags":[5436,2662],"class_list":["post-145676","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-es-noticia","category-sociedad","tag-cepa-manaos","tag-coronavirus"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Detectaron la cepa Manaos en la ciudad rionegrina de General Roca - Diario Textual<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/diariotextual.com\/inicio\/index.php\/2021\/05\/12\/detectaron-la-cepa-manaos-en-la-ciudad-rionegrina-de-general-roca\/\" \/>\n<meta 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